Human Growth Hormone Research Study
hgh human growth hormone research study
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Human Growth Hormone Research Study
Dr. Klatz is one the the foremost authorities on HGH.
The excerpts below are from his book- Grow Young with HGH.
Oral Growth Hormone Study
Babak Parisan M.D. of the Bushard Medical Group clinically evaluated and assisted in a six-month study involving the administration of a polymer matrix oral spray Human Growth Hormone delivery system.
200 healthy patients were screened and tested (112 females and 88 males).
IGF-1 testing is presently the standard accepted protocol for evaluating the level of human growth hormone in the blood.
Patients were pre-examined to determine a baseline IGF-1: 114.26 ng/ml in females (average age 51) and 135.22 ng/ml in males (average age 48).
No change in diet was advised, however it was noted that all patients ate an average of 3 meals per day with approximately 3000 calories.
Testing began with a prescribed dosage of 2000 nanograms in the morning within one hour of awakening, and 2000 nanograms in the evening immediately before retiring (totalling 4000 ng of HGH per day, seven days a week).
30 days after inception, testing showed that patients’ IGF-1 levels were elevated 30% over baselines: 149.85 ng/ml in females and 176.31 ng/ml in males.
After 60 days, IGF-1 levels were tested again and shown to be 53% over baselines: 175.63 ng/ml in females and 209.59 ng/ml in males.
At the end of the 6 month study, IGF-1 levels had increased over 102% over baseline in females (232.12 ng/ml) and 109% over baseline in males (284.05 ng/ml).
Cholesterol levels were diminished in 94 patients by an average of 14.8%, and triglyceride levels were also reduced by 31%.
Improvements were noted in mental stability, muscle accretion, weight reduction, energy level, libido, epidermis rejuvenation, and reacquired hair color and density.
In all 200 patients no adverse side effects were reported or observed.
The study suggests that the use of the 191 amino acid growth hormone molecule administered in a sublingual application is an effective method for encouraging and promoting the rejuvenation of cellular tissues.
Excerpts from Grow Young With HGH
No More Grumpy Old Men (or Women)
What if I told you could live to be age one hundred in as healthy and vigorous condition as you are now?
Or if you are already suffering the ill effects of aging, you could turn back the clock twenty years and stay that way until the century mark?
Would you be interested?
And what if that extra thirty years added to the average life span allowed you to live long enough to take advantage of new scientific breakthroughs so that your healthy functional life span could be extended to 120 or 130 years and beyond?
And what if the launching pad to that wonderful prospect involved taking a substance that caused your body to lose unwanted fat and build muscle, renew your organs, improved your heart and lung activity, made studs out of men, increased sexual pleasure in women, and gave you the energy, sleep, and wonderful sense that the world is your oyster?
Would you say, “What is this substance and how can I get some?”
There is such a substance.
It is an Alice-in-Wonderland kind of hormone.
Too little of it makes us dwarfs and too much of it turns us into giants.
But the right amount of it at the right time promises to bring about the most fundamental revolution in society today–the beginning of the end of aging.
The “Fountain of Youth” Hormone
On July 5, 1990, the prestigious New England Journal of Medicine published a clinical study on a drug that sent shock waves throughout the world.
It was instantly hailed as a fountain of youth. In a scene that seemed like something out of the movie Cocoon, injections of synthetic human growth hormone–a substance naturally produced by the pituitary gland–had turned twelve men, ages sixty-one to eighty-one, with flabby, frail, fat-bulging bodies, into their sleeker, stronger, younger selves.
In language rarely used in conservative medical journals, Daniel Rudman, M.D., and his colleagues at the Medical College of Wisconsin wrote:
“The effects of six months of human growth hormone on lean body mass and adipose-tissue mass were equivalent in magnitude to the changes incurred during 10 to 20 years of aging.”
In interviews with reporters, the men in the study and their wives reported other startling changes.
The gray hair of a sixty-five-year-old man was turning black.
The wife of another man had trouble keeping up with her newly energized husband even though she was fifteen years younger.
A third man, who saw the wrinkles disappear on his face and hands, was now opening jars with ease, passing younger people on the street, and gardening for hours on end.
Some of the users and their spouses made sly references to reinvigorated sex lives.
What happened to the control group? In group 2, as they were called in the study, “there was no significant change in lean body mass, the mass of adipose tissue, skin thickness, or bone density during treatment.”
In other words, they continued aging on schedule.
Double-Blind Clinical Proof
Drugs and therapies that claim to reverse aging are nothing new.
For decades youth seekers have trekked to the four corners of the world seeking youth and immortality.
Recent examples include Ana Aslan’s clinic in Rumania for injections of Gerovital H3, which is essentially the same Novocain your dentist uses. Konrad Adenauer, Gloria Swanson, Groucho Marx, and more than 50,000 lesser-known patients have had their buttocks shot with fresh fetal lamb cells at Clinique La Prairie in Switzerland.
Others swear by ginseng or placental extract or nucleic acid therapy, which unleashed a craze for eating RNA-rich sardines.
While some of these therapies might have genuine merit, none of them has passed the gold standard of drug testing: controlled, randomized, double-blind clinical study.
Today there is immense interest in the hormone melatonin, released by the pineal gland in the brain. But melatonin has yet to be tested in double-blind trials in human beings.
The only age-reversing drug that has passed placebo-controlled double-blind clinical trials with flying colors is human growth hormone.
Not once, but many times over.
HGH Today
Following up his own work, Rudman found that HGH given to twenty-six elderly men re-grew the livers, spleens, and muscles that had shrunken with age back to their youthful sizes.
Improved muscle strength, he pointed out, could make the difference between someone’s being on his feet or being confined to a wheelchair, between being spoon-fed or cooking a meal, between living independently or living in a nursing home.
“The overall deterioration of the body that comes with growing old is not inevitable,” he concluded.
“We now realize that some aspects of it can be prevented or reversed.”
Rudman’s landmark discovery opened the floodgates to the point that there are now thousands of studies in the world medical literature documenting the benefits of growth hormone therapy.
The National Institute on Aging has funded a multimillion-dollar effort in nine medical centers that will run for five years to test whether human growth hormone and other trophic factors–defined as substances that promote growth or maintenance of tissues–can reverse or retard the aging process.
In 1992 medical researchers at Stanford University stated, “It is possible that physiologic growth hormone replacement might reverse or prevent some of the ‘inevitable’ sequelae of aging.”
But many people are not waiting for the results of these studies. In this country and abroad, doctors at dozens of clinics are treating thousands of old and middle-aged people who wish to erase the effects of aging.
Hundreds of case histories have now become available, some of which you will read about in the coming chapters.
As we go to press, the FDA has just approved HGH for use in adults.
Until now the only indication had been for treatment of children who failed to grow due to lack of growth hormone.
The adult indication is for somatotrophin (growth hormone) deficiency syndrome (SDS). Signs of SDS include decreased physical mobility, socialization and energy levels, along with a greater risk of cardiovascular disease and lower life expectancy.
