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Retin-a Cream Acne Medication Information
RETIN-A (tretinoin gel
0.1%) is proven to reduce the severity of acne vulgaris in effected
patients. Seen most commonly in adolescents, but also seen in older
patients as well, true acne involves the formation of comedones (large
deep seeded pus filled pimples) that resolve slowly leaving behind a deep
scar. RETIN-A can significantly reduce the severity of these
lesions.
HOW DOES RETIN-A CREAM WORK?
RETIN-A acts primarily by modifying the abnormal keratinization
(formation of the superficial layer of skin) located around hair
follicles. Comedones (large deep seeded pus filled pimples) form in
follicles with an excess of keratinized superficial skin cells.
RETIN-A promotes the detachment of these excess cells and the
enhanced shedding of these cells from the follicular base. Through this
action, comedo contents are emptied and the formation of new comedones is
significantly reduced.
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HOW TO USE THIS ACNE MEDICATION:
Apply a thin layer to affected
areas at bedtime. Use a gauze pad or cotton swab to apply the liquid. Wash
your hands immediately after use. Using this medication more frequently or
in excessive amounts does not improve the results, but may increase side
effects. Avoid applying near the eyes, mouth, or open cuts since this
medication can irritate sensitive skin. Acne may appear to worsen when the
medication is first used; continue therapy. It may take three to six weeks
before the full benefits of this medication are seen.
HOW EFFECTIVE IS RETIN-A ACNE MEDICATION?
In a number of different clinical
studies, RETIN-A was significantly superior to a control gel in
decreasing comedo count. Taken together approximately 25% of patients
achieved superior results with the use of this medication.
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RETIN-A AND ROGAINE?
Yes, when applied topically to the
scalp RETIN-A can induce hair regrowth and significantly augment
the activity of ROGAINE.
It is postulated that this effect
is due to increased absorption of ROGAINE through the scalp by an
alteration of the stratum corneum (superficial layer) barrier. One study
demonstrated that 0.05% RETIN-A tripled the absorption of
ROGAINE locally over effected areas, when compared with a control
drug.
CAN I USE COSMETICS IF I AM ALSO USING RETIN-A?
Cosmetics may be used, but clean
skin thoroughly before applying RETIN-A.
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USE DURING PREGNANCY:
RETIN-A is applied to the
skin. Usually, less than 10% of RETIN-A passes into the mother's
bloodstream, and even less reaches the baby. Broken skin, using more than
is needed on an area, or use on a large area will cause more of the
RETIN-A to pass through the skin. In general, the less
RETIN-A that is used on the mother's skin, the less likely there
will be risks to the baby.
Several studies have tried to find
out the effects of RETIN-A on pregnancy. These studies have not
found that babies whose mothers used RETIN-A during pregnancy are
any more likely to have birth defects than babies whose mothers did not
use RETIN-A.
Nonetheless, it may be best to
reserve RETIN-A use during pregnancy for only the most severe cases
of Acne Vulgaris. Even then, it should be used with extreme
caution.
SIDE EFFECTS:
RETIN-A may also
cause itchiness and scaling of the skin. This can sometimes be very
extreme depending on the individual. Most people will experience some
itching or scaling if too much RETIN-A is applied.
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CAUTIONS:
This medication can increase
sensitivity to sunlight, wind and cold. Avoid prolonged exposure to the
sun and sunlamps. Wear protective clothing and use an effective sunscreen.
This medication should be used during pregnancy only if clearly needed. It
is not known if RETIN-A appears in breast milk. Consult your doctor
before breast-feeding. Use mild soap when washing your face. Do not wash
face excessively. Abrasive soaps, cleansers, medicated creams or lotions
can increase skin irritation. Use other acne preparations with caution
while using RETIN-A.
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